Beat it

Beat it

Diabetes drug won't help obese kids keep off weight


By Rachael Rettner
Few children who become obese are able to lose and keep off weight with diet and exercise alone, leading some doctors to prescribe drugs, such as the diabetes drug metformin, to treat childhood obesity. However, a new study suggests that metformin may not help kids and teens without diabetes lose weight over the long term.
The study, which reviewed information from previous research, found no evidence that children and teens who took the drug lost more weight after one year than those who did not take the drug.
While some adolescents who took the drug did experience short-term weight loss  (six months or less), the effect was modest, and it's not clear whether such limited weight loss would actually improve their health, the researchers said. [Lose Weight Smartly: 7 Little-Known Tricks That Shave Pounds ]
Given the current evidence, metformin has not been shown to be superior to other weight-loss treatments for kids, such as diet and exercise, the researchers said.
"Unfortunately, this drug is not going to be the answer," said study researcher Marian McDonagh, of Oregon Health & Science University. Overall, the drug does not appear to provide enough weight reduction for children to experience meaningful health benefits in the long term, McDonagh said.
Still, it's possible that certain groups of children, such as those who are very obese, may benefit from taking the drug. A large study is needed to identify these groups, the researchers said.
The study analyzed information from 14 previous studies (eight in the United States and others in Canada, Australia, Mexico, Europe, Iran and Turkey), which included a total of 946 children ages 10 to 16 who did not have diabetes. The children's body mass indices (BMIs) ranged from 26 to 41. In most studies, children who took metformin also engaged in lifestyle changes aimed at helping them lose weight.
On average, children who took metformin  for six months achieved a 3.6 percent greater reduction in their BMI compared with those who practiced lifestyle changes alone.
However, studies in adults suggest that, in order for a weight-loss treatment to lead to meaningful improvements in health down the road, it needs to reduce BMI by 5 to 10 percent, McDonagh said.
Children in the studies who took metformin for a year saw about the same decrease in BMI as those who practiced lifestyle changes alone. And after one year, both groups started to slip back to their original weight.
The researchers would like to see more studies on weight-loss treatments that involve a child's entire family. It's possible that family-based interventions may help children lose more weight  whether they are taking a drug or not than interventions that don't consider the child's family, McDonagh said.
Metformin is approved by the Food and Drug Administration to treat children and adults with Type 2 diabetes .
The new study was published Dec. 16 in the journal JAMA Pediatrics.


Gene Deficiency Linked With Diabetes And Liver Cancer In Males


A gene deficiency could be the culprit for both liver cancer and diabetes for some men, according to a new study from researchers at Michigan State University.
Researchers broke down the genomes of a pool of mice, discovering that one particular gene, NCOA5, was linked to massive spikes in both conditions for males.
Though both males and females carry this gene, it was only linked with a spike in males for whom the gene if deficient. Males in that category were at a 94 percent increased risk of developing liver cancer compared with all other mice. They also found a glucose intolerance in 100 percent of the males with the deficient gene.

"Because estrogen may function through the NCOA5 gene and previously has been found to play somewhat of a protective role against both diseases, the result is a decreased risk in females," the researchers said. "Since males produce lower amounts of estrogen, this can contribute to their susceptibility." 

Vitamin D May Reduce Pain, Depression For Women With Type 2 Diabetes



Increased levels of Vitamin D may provide various benefits to women suffering from Type 2 diabetes, according to researchers from the Department of Psychiatry and Behavioral Neurosciences at the Loyola University Chicago Stritch School of Medicine.
Researchers enlisted a group of women with type 2 diabetes to take a 50,000-IU vitamin D2 supplement every week for a period of six months. They found that those women suffering from depression along with diabetes saw a significant dip in their depression symptoms. They also found an overall drop in reported pain levels.
"Pain is a common and often serious problem for women with type 2 diabetes and depression. While further research is needed, D2 supplementation is a promising treatment for both pain and depression in type 2 diabetes," the researchers said. "Vitamin D has widespread benefits for our health and certain chronic diseases such as Type 2 diabetes. This NIH grant will allow us to shed greater light on understanding the role that this nutrient plays in managing the health of women with diabetes." 

Diabetes link with dementia to be examined


December 11th, 2013
It is well known that type 2 diabetes raises the risk of dementia. The reasons for this are less clear, but one explanation could be insulin resistance in the brain, according to Malin Wennström, a researcher at Lund University's Molecular Memory Research Unit. She has received EUR 700,000 from the Swedish Research Council to investigate her theory.
"The goal is to find measureable biomarkers early in the development of dementia in diabetes patients and, in the long term, to develop drugs that can halt the process", says Malin Wennström.
Type 2 diabetes often goes hand in hand with insulin resistance, a condition that weakens the effect of insulin on body tissue, for example in muscle and fat cells. In recent years, researchers have come to understand that cells in the brain also develop insulin resistance.
The focus of Malin Wennström's research is on pericytes, a type of cell that enwraps small blood vessels in the brain. Pericytes are found throughout the body and have an important supporting function for blood vessels.
"We know that loss of pericytes is the first abnormality of the diabetic eye which can be observed clinically. Without pericytes, blood vessels become fragile and start to leak, which in time leads to poorer blood supply", says Malin Fex, a researcher at Lund University Diabetes Centre, who is also participating in the project.
One explanation as to why patients with type 2 diabetes are twice as likely to develop dementia later in life compared with non-diabetics could thus hypothetically be a loss of pericytes in the brain caused by insulin resistance.
"In one of the most common forms of dementia – vascular dementia – blood circulation in the brain is weakened, and a high proportion of Alzheimer's patients also show vascular pathology", says Malin Wennström.
The research will be carried out in three phases:
In Phase A, pericytes isolated from deceased dementia patients will be cultured and studied.
"We will stimulate the pericytes with factors that we know lead to insulin resistance, for example high levels of inflammatory signal molecules, high levels of sugar and fat, and stress hormones. We will then study the response of the pericytes by measuring changes in gene expression, protein release and levels of insulin resistance. In this way, we hope to find new biomarkers that can signal insulin resistance and other changes in the pericytes", says Malin Wennström.
In Phase B, the experiments will be transferred to laboratory animals. Insulin-resistant rodents with diabetes and rodents that have been exposed to chronic mild stress and systemic inflammation will be studied. The levels of biomarkers discovered in Phase A will be measured in the rodents's blood and cerebrospinal fluid. By simultaneously studying the brains of the rodent, the researchers can investigate whether the biomarkers reflect the biological processes induced by insulin resistance in the brain.
"The studies on cells give us insights into specific mechanisms, but to get a picture of what they look like in a complex biological system, we have to complement the studies with animal experiments."
In the final phase, Phase C, the discoveries that have been made will be tested in clinical studies. Working with Katarina Nägga, a doctor at the Memory Clinic in Malmö, samples of blood and spinal fluid from dementia patients and blood from individuals who have undergone a glucose tolerance test (a test that measures changes in the sugar metabolism that can be a sign of insulin resistance) will be analysed.
"Analysing cerebrospinal fluid is one of the few methods of studying changes in the human brain associated with disease", says Malin Wennström, adding:
"The best outcome would be if we found markers for this in the blood. We could then easily identify at an early stage, which individuals with type 2 diabetes are at increased risk of developing dementia in the future. We would then also have a concrete target for the development of treatments to halt the process."
Provided by Lund University








Mental Disorders Linked To Increased Risk of Heart Disease




Men suffering from mental disorders such as schizophrenia are more likely to develop heart disease, according to research at the University of Edinburgh, the University of Southampton and the Karolinska Institute.
The study, published in the journal Circulation, surveyed more than a million Swedish men over a 22-year period beginning at the average age of 18.
Those at the highest risk were men who had been hospitalized with a mental condition, the study found.
"Our findings suggest that mental disorders pose a huge public health burden in terms of premature illness and death due to coronary heart disease," study researcher Catharine Gale said. "The physical health care of people with mental disorders needs to be a priority for clinicians if this burden is to be reduced."
The team found increased risk for a range of mental disorders including schizophrenia, bipolar disorder, depression, neurotic disorders, personality disorders and substance-use disorders. 

Diabetes can have no-symptom 'honeymoon period'


By Dr. Keith Roach , Herald-Tribune

DEAR DR. ROACH: My 13-year-old son was diagnosed with Type 1 diabetes on March 7, 2012, at the University of Michigan Hospital in Ann Arbor, Mich., and his A1C was 12. Of course, I prayed for a miracle, and about one week after he was diagnosed, I started him on a nutraceutical called Protandim. After 17 days of being on Protandim, he came off of insulin and has been off ever since. His doctor says it's a "honeymoon period" and that it will not last. I asked him how long a honeymoon typically lasts and he said, "Days, weeks, months, but not years." I've told his doctor about the product, but he does not believe there is any correlation between taking it and my son not needing insulin. His A1C went from 12 down to 6.5 within three months, and then it was 7.0 and then 7.5, and we still check his sugar and monitor his diet not allowing him to have too many carbohydrates, nor do we allow him to have real sugar, but he takes one Protandim per day. All of the information I have researched this drug shows that it does help with diabetes that would be Type 2 and also Type 1, especially if caught early. A different doctor explained that Protandim helps repair the islet cells over time. -- M.A.

ANSWER: I have heard of Protandim, but was unable to find any research showing that it improves diabetes care. It is supposed to prevent aging, but the evidence that it works is sparse.
I think that your son probably is in a prolonged honeymoon period, which occasionally can last for years. The careful diet he is on certainly is helping as well. However, with the A1C (a measurement of average blood sugar over a few months) rising, and now in the frankly diabetic range (normal is less than 6.5 percent), I think he will very shortly need to be back on insulin.
It is almost impossible to say in any given person whether a medication or supplement is effective. I can't recommend this supplement based on your son's experience, even though it sounds very promising. I will be watching carefully for any peer-reviewed articles on this subject.

Diabetes has become epidemic in North America. The booklet on it provides insight on its diagnosis and treatment. Readers can order a copy by writing: Dr. Roach -- No. 402, Box 536475, Orlando, FL 32853-6475. Enclose a check or money order (no cash) for $4.75 U.S./$6 Can. with the recipient's printed name and address. Please allow four weeks for delivery.


Dr. Roach regrets that he is unable to answer individual letters, but will incorporate them in the column whenever possible. Readers may email questions to ToYourGoodHealth@med.cornell.edu or request an order form of available health newsletters at P.O. Box 536475, Orlando, FL 32853-6475. Health newsletters may be ordered from www.rbmamall.com.


New Study Proves That Healthier Diets Are More Expensive


It may be far more expensive to maintain a healthy diet than an unhealthy diet, according to researchers from the Harvard School for Public Health. For the study the researchers reviewed data collected from 10 wealthy nations between 2000 and 2011.
They found that on average, those who maintain a healthy diet rich in fruits, vegetables and whole grains are spending about $550 a year more on their diet. Though the cost associated with healthy food has often been suggested by researchers, this is the first study to scientifically analyze the phenomenon:

"People often say that healthier foods are more expensive, and that such costs strongly limit better diet habits. But, until now, the scientific evidence for this idea has not been systematically evaluated, nor have the actual differences in cost been characterized," the researchers explained. 

New Study Proves That Healthier Diets Are More Expensive


It may be far more expensive to maintain a healthy diet than an unhealthy diet, according to researchers from the Harvard School for Public Health. For the study the researchers reviewed data collected from 10 wealthy nations between 2000 and 2011.
They found that on average, those who maintain a healthy diet rich in fruits, vegetables and whole grains are spending about $550 a year more on their diet. Though the cost associated with healthy food has often been suggested by researchers, this is the first study to scientifically analyze the phenomenon:

"People often say that healthier foods are more expensive, and that such costs strongly limit better diet habits. But, until now, the scientific evidence for this idea has not been systematically evaluated, nor have the actual differences in cost been characterized," the researchers explained. 

absolutely blogalicious: 'Gourmet Junk Food' Was One Of The Worst Ideas Of ...

absolutely blogalicious: 'Gourmet Junk Food' Was One Of The Worst Ideas Of ...: Honest Burgers. Dirty Burger. Patty & Bun. Burger & Lobster. Slider Bar. Almost Famous. Lucky Chip. Mother Flipper. And, the dadd...

absolutely blogalicious: Condiments

absolutely blogalicious: Condiments

absolutely blogalicious: Time to eat

absolutely blogalicious: Time to eat

absolutely blogalicious: Baking powder

absolutely blogalicious: Baking powder

absolutely blogalicious:

absolutely blogalicious:

absolutely blogalicious: Gourmet doughnuts are Dallas’ latest food trend

absolutely blogalicious: Gourmet doughnuts are Dallas’ latest food trend:   Gourmet doughnuts are Dallas’ latest food trend DALLAS — Doughnuts are the new cupcakes, or so the saying goes. All over the countr...

absolutely blogalicious: F. Scott Fitzgerald’s 13 Preposterous Ideas for Yo...

absolutely blogalicious: F. Scott Fitzgerald’s 13 Preposterous Ideas for Yo...:  “At this post holiday season, the refrigerators of the nation are overstuffed with large masses of turkey, the sight of which is ca...

Hot Tub Spa Dealer Shares Health Tips for Diabetes Month



Hot Tub Sale Malibu, CA, Supports American Diabetes Month by Sharing Suggestion on how to Control Diabetes. Offers Free Hot Tub Test Soaks to Thousand Oaks, CA Residents.

Thousand Oaks, CA, December 02, 2013 --(PR.com)-- Spa-Warehouse, a premier hot tub and spa dealer in Ventura and Thousand Oaks and Malibu area selling MAAX portable spas, publishes 3 tips for American Diabetes Month.

“Diabetes is a disease on the rise,” said Jim Vishnefske, president of Spa-Warehouse. “With November being American Diabetes Month, there’s no better time to try and find the best ways to battle this disease,” continued Vishnefske. Here are the three ways to control diabetes.

Drink It Away - The average American consumes roughly 152 pounds (yes, pounds) of sugar every year according to studies by the DHHS, United States Department of Health and Human Services. Of that massive amount of sugar, over 33% of it is consumed in the form of sugary drinks like soda. A study by the European Prospective Investigation into Cancer and Nutrition from the Imperial College of London showed that just a single serving of any type of sugar sweetened sodas per day increases the overall risk of Type II Diabetes by as much as 22%.

While fresh, plain water is always the best alternative for providing hydration to the body, it is still possible to enjoy a relaxing beverage without boosting sugar levels. Substitute a warm glass of green tea for sugary sodas and even caffeine filled coffee or black teas. Plain green tea provides lots of taste and many extra health bonuses as well, such as a high level of antioxidants.

Work It Off - Controlling diabetes means learning how to get rid of the couch potato mentality. Exercise plays as much of a role in blood sugar regulation as a good diet does. According to the American Diabetes Association, regular activity boosts metabolism to help the body absorb and use nutrients more efficiently and it increases the cellular sensitivity to insulin so the body uses it better.

The first step is just getting started. For many Americans not used to daily exercise that can be the biggest hurdle. Finding exercise solutions that are enjoyable can make a big difference in how likely a person is to continue with the program, so don’t pick an exercise based solely on how effective it will be in battling diabetes at first. Even something as simple as walking around the block everyday is a good start.

However, for the best exercises to beat diabetes, high intensity workouts are the goal. The ADA recommends 30 minutes of intense aerobic work 5 times per week.

Soak It Away - Dr. Philip L. Hooper, MD from the McKee Medical Center studied the effects of hot water therapy from hot tubs on blood sugar levels, and found it especially helpful for those patients who could not exercise. The study published in the New England Journal of Medicine showed that soaking 30 minutes per day in a hot tub, at least six days per week for three weeks effectively lowered blood sugar averages in the patients and also helped decrease weight levels by 3 to 4 pounds.

The study also showed that soaking in a hot tub had more beneficial effects than swimming, and was superior to simply soaking in a warm bath tub due to the fact that hot tub waters are regulated to maintain the level of heat. Diane Pearson, RN suggests that hot tubs also add a level of socialization that makes them a great way for individuals to get the benefits in a way they are most likely to maintain and continue.

Because of the relaxing effects of a hot tub, it is best to pursue this type of therapy in the evening. Soaking for 30 minutes before bed also provides a good foundation for a great night’s sleep.

Hot Tubs Thousand Oaks, Hot Tub Sale Malibu, CA

People wanting to learn more about hot tubs are encouraged to visit the company website and pick up a copy of their free report “Insider Secrets to Choosing the Best Hot Tub" Visit, http://www.Spa-Warehouse.com/

“To help local residents understand how portable spas, hot tubs and swim spas can help improve overall health and well-being, Spa-Warehouse will provide free hot tub test soaks during the entire month,” commented Vishnefske. “We want to encourage local residents to check out the benefits of a relaxing soak in the soothing waters of a hot tub for themselves,” said Vishnefske.

About Spa-Warehouse
Spa-Warehouse, we take great pride in offering on spas that are “Made in America.” As an A+ rated member of the BBB we offer our customers a comfortable, inviting buying experience and we offer no-cost on-site home inspection prior to placing the order for your spa.

With a proven reputation of over 40 years of expertise in luxury hot water relaxation products, we represent the MAAX family of products including Elite Spas, and VITA Spas, California Cooperage Hot Tubs as well as the PowerPool Swim Spas. Our variety of spas, give you a wider selection of features, design and style of spas all from the same manufacturing facility in Chandler, AZ.

To learn more, pick up a copy of their free report “Insider Secrets to Choosing The Best Hot Tub" Visit, http://www.Spa-Warehouse.com/ or call (805) 654-9000.


Turning Up The Heat Could Help Fight Weight Gain


Those who live in well-heated homes are less likely to be obese and have lower BMIs than those with cooler houses, according to research conducted at the University of Stirling in Scotland. The study, published in the journal Obesity, surveyed data on 100,000 adults culled during the Health Survey for England.
The subjects who lived in warmer homes - i.e. with temps consistently above 73.4 degrees - had lower BMI levels than those with cooler homes.
"We set out to investigate the scientific claims that cooler indoor temperatures help us maintain a healthy weight by pushing our bodies to expend more energy through shivering and generating heat through tissues. In fact, the research suggests people may eat less and burn more energy when residing in a warmer indoor environment," wrote Michael Daly, the study's author.

He added that the temperature range of 68.5 to 73.4 degrees provides an atmosphere in which most people are neither warm nor cold. 

Health Tip: Keep Diabetes in Check


                       
-- It can be difficult to eat healthy during the holidays, especially for diabetics.
The U.S. Centers for Disease Control and Prevention offers  these suggestions for people with diabetes:

•           Eat a healthy snack before you attend a holiday gathering, or pack a healthy snack to eat there. You can also ask ahead of time which foods will be served, so you can better plan.
•           If there's a buffet, take small portions, then head to another room so you're not tempted to reload your plate.
•           Choose low-calorie or calorie-free drinks, from unsweetened tea to sparkling water. If you drink alcohol, drink a small amount with food.
•           Avoid foods such as glazed ham, turkey with gravy and side dishes laden with butter, cream or mayonnaise. Instead, opt for lighter dishes with a vegetable base and fewer fatty, sugary and salty ingredients.
•           For dessert, choose a food with a fruit base instead of desserts high in sugar, fat and cholesterol.
•           Focus on friends and family, not food.


Diabetes rise increases amputation danger


An expert has warned Australians are risking blindness by not taking type 2 diabetes seriously. Source: AAP

AUSTRALIANS are risking amputations, kidney failure and blindness by not taking type 2 diabetes seriously, says a leading specialist on the disease.
Diabetes is one of the greatest health epidemics in modern times, says Associate Professor Neale Cohen, General Manager of Diabetes Services at the Baker IDI Heart and Diabetes Institute.
"People need to take a lot more responsibility for their health.
"It's a worldwide problem largely driven by sedentary lifestyle and unhealthy eating, said Prof Cohen, who is making several presentations at a world diabetes congress in Melbourne from Tuesday.
Australia has parallel epidemics. For most, type 2 diabetes is caused by too much food and too little exercise, with an added genetic risk for some.
Indigenous people, however, are at serious risk regardless of their lifestyle.
"It's a national tragedy," said Prof Cohen.
"Really these communities do not eat a lot worse than other Australians.
"But they get an extremely aggressive form of type 2 diabetes that can occur at a young age.
"The kidney failure rate is so extreme that Alice Springs has one of the largest kidney dialysis units in the southern hemisphere."
Prof Cohen said people liked to blame carbohydrates for diabetes, but the real danger food was fat.
"People are generally surprised that olive oil or avocados are not particularly good for diabetes or weight."
It would be a great start if high-risk and diabetic people reduced the fat in their diet and limited the number of times they ate out, he said.
"Most takeaway foods are high in fat. Most restaurant food is much higher in fat than we should be eating."
A big problem is that many people do not know their diabetes status and those who do often do not take it seriously.
"You can't see it or feel it. But it is a serious condition.
"If people are told they have cancer they get really upset and worried.
"Often when people are told they have diabetes they are fairly relaxed. They don't realise how serious it is."
High-risk people should have a fasting glucose test every year, he said.
"People may have had it for five or 10 years before they get tested. They could have kidney damage or bleeding at the back of the eyes.
"They could have had a heart attack."


Childhood Exercise May Lower Effects Of Maternal Obesity


Exercise during adolescence may help mitigate the negative health effects shown in children whose mothers had high-fat diets during pregnancy, according to an animal study conducted at Johns Hopkins.
The team compared a group of rat offspring whose mothers were given high-fat diets during pregnancy. The group that was exercised often weighed the same as its counterparts - but it had fewer fat deposits and the brains were better able to respond to a hormone known to suppress the appetite.
"Just three weeks of exercise early in life had a persistent effect on the satiety centers of the brains of these rat pups. If we can find a way to take advantage of that phenomenon in humans that would be great, because preventing obesity is probably going to be much easier to do than reversing it," said lead author Kellie L.K. Tamashiro.

She added that early exercise may hold the key to maintaining a strict exercise regiment throughout adulthood. 

Breast Cancer Linked To High-Fat Diets During Puberty



Adolescent women who consume diets high in fat may be putting themselves at a higher risk for breast cancer later in life, according to research conducted at Michigan State University. The study, published in the journal Breast Cancer Research, was conducted on mice who were given high fat diets.
Just three weeks after the dietary change, the mice began to show changes in the breast, such as increased cell growth and alterations in the immune cells.
In addition, the diet produces a gene signature in the tumors consistent with a subset of breast cancers known as basal-like, which often carry a worse prognosis.
"This is very significant because even though the cancers arise from random mutations, the gene signature indicating a basal-like breast cancer shows the overarching and potent influence this type of diet has in the breast," said Sandra Haslam, physiology professor at MSU's College of Human Medicine.


New Protein May Trigger Fat Burning


11/28/2013 12:15 PM ET
Scientists have discovered a protein that could trigger the burning of fat in the body. In the study, carried out by a research team at the University of Veterinary Medicine in Vienna, scientists found that a specific chemical compound can activate an uncoupling protein called UCP1 (found in brown fatty tissue) which could trigger fat burning in adults.
Study researcher Elena Pohl noted: "If we can find out how to regulate this protein, we might also find a way to trigger fat burning in the body."
Dr. Pohl was careful to add, however, that previous attempts at using substances similar to UCP1 to accelerate the human metabolism have caused patients serious or lethal side effects, with the products pulled from the market.
Nonetheless, she said: "If we are able to regulate UCP1 in a controlled way, it might be different story."
The results of the study are published in the journal "PLOS One

Obesity, Poor Metabolic Health Raise Risk Of CVD


Obese individuals and normal weight individuals who are metabolically unhealthy face a greater risk of cardiovascular disease, according to research conducted at the University of Texas.
The study, published in the Journal of Endocrinology and Metabolism, analyzed the results of the San Antonio Heart Study.
Metabolic unhealth is established by elevated blood pressure, elevated triglyceride and glucose levels, insulin resistance and decreased high-density lipprotein levels.
"Risk of developing diabetes rose in a stepwise fashion with increasing BMI," although "only metabolically healthy individuals had a graded increase in incident cardiovascular disease," wrote the study's authors.
"The risk of developing DM and CVD is increased in MUH-NW and MHO individuals. Screening for obesity and other metabolic abnormalities should be routinely performed in clinical practice to institute appropriate preventive measures," the authors added. 

Today's Children Are Fatter And Slower Than Previous Generation

  
Kids today are slower and less fit than their parents at the same age, according to research conducted by the American Heart Association. The study analyzed 50 previous studies taken between 1964 and 2010 that involved more than 25 million kids, ages 9 to 17, in 28 countries.
The team found that today's children are roughly 15 percent less aerobically fit than their parents at their age, and that their cardiovascular endurance has fallen about 6 percent per decade between 1970 and 2000.
"The most important type of fitness for good health is cardiovascular fitness, which is the ability to exercise vigorously for a long time, like running multiple laps around an oval track," said Grant Tomkinson, Ph.D., lead author of the study.
"We need to help to inspire children and youth to develop fitness habits that will keep them healthy now and into the future. They need to choose a range of physical activities they like or think they might like to try, and they need to get moving."

The study also found that in a mile run, kids today are about a minute and a half slower than their peers 30 years ago. 

Life May Be Prolonged By Eating Nuts Every Day


People who eat a handful of nuts each day may increase their life span, according to research conducted at the Dana-Farber Cancer Institute, Brigham and Women's Hospital, and the Harvard School of Public Health. The study, published the New England Medicine of Journal, surveyed data on nearly 120,000 people over a 30-year period.

The nut eaters were more slender than their non-nut eating counterparts, and less likely to suffer from the most common/dangerous health risks, the study showed.
"The most obvious benefit was a reduction of 29 percent in deaths from heart disease - the major killer of people in America," said Charles S. Fuchs, MD, MPH, director of the Gastrointestinal Cancer Treatment Center at Dana-Farber, the senior author of the report.
"But we also saw a significant reduction - 11 percent - in the risk of dying from cancer," added Fuchs, who is also affiliated with the Channing Division of Network Medicine at Brigham and Women's.

The team found that several types of nuts (e.g. walnuts, hazelnuts, almonds, Brazil nuts, cashews, macadamias, pecans, cashews, pistachios and pine nuts) brought the same benefits to their consumers

Lower Brown Fat Content May Put Asians At Risk For Diabetes

People of Asian descent may be at an increased risk for diabetes because of a lack of brown fat cell or brown adipose tissue, according to a new study from researcher in the Netherlands.

BAT cells are created as a means to store the body's excess energy, but unlike white fat cells they are burned to create heat when the body is cold. To examine the lack of BAT cells on Asians, the researchers compared 12 Asian men to 12 Caucasian men. Overall, the Asian men had 34 percent less BAT than the white men, and they resting energy consumption was also lower.

This lower energy consumption could also be linked with a decrease in the clearance of glucose for the blood, which is trigger of diabetes:

"We recently showed that BAT can be recruited in humans following 10 days of cold intervention. Future studies should be directed towards the efficacy of this strategy, as well as other options, such as medication, to increase BAT volume or activity," the researchers said. 

Diabetes kills 1 person every 6 seconds, expected to rise 55%




By Albertina Torsoli, Bloomberg NewsBloomberg

GENEVA — Diabetes kills one person every six seconds and afflicts 382 million people worldwide, according to the International Diabetes Federation, which has been canvassing the help of people ranging from celebrity chef Jamie Oliver to Bob Marley's nephew to raise awareness about the problem.
The number of diabetes cases has climbed 4.4 percent over the past two years, according to new figures the Brussels-based federation released Thursday. The number of people affected by the disease is expected to climb 55 percent to 592 million by 2035 as factors including poor diet, a more sedentary lifestyle, increases in obesity and life expectancy fuel an epidemic, it said. There were only 285 million sufferers worldwide in 2009.
"We haven't seen any kind of stabilizing, any kind of reversal," Leonor Guariguata, an epidemiologist and project coordinator for IDF's Diabetes Atlas, published every two years, said in a phone interview. "Diabetes continues to be a very big problem and is increasing even beyond previous projections."
The disease, caused by a lack of insulin the body needs to convert blood sugar into energy, is becoming a financial burden on governments, and led to $548 billion in global health-care spending this year, the federation said. To counter the surge, it recommends policy makers across many sectors should devise concerted action.
Jamie Oliver and Charles Mattocks, Bob Marley's nephew, are among celebrities that have been helping IDF advocate the need for healthy living. TV celebrity Oliver, who has sold more than 30 million cookbooks and owns restaurants from London to Sydney, has appeared in IDF's magazine Diabetes Voice while Mattocks, also a chef, is currently touring the U.S. in a camper to speak about the benefits of a healthy lifestyle and eating habits.
"It's all about awareness, awareness and awareness," Mike Doustdar, Senior Vice President of Novo Nordisk, the world's biggest insulin maker, said during a webcast co-hosted with IDF before the announcement. "Diabetes is a silent disease, so the best thing we can do about it is to talk about it."
The call is not going unheard. Health officials from almost 200 countries in May adopted nine targets, such as reducing average daily salt consumption by 30 percent by 2025, in a bid to fight cancer, heart disease and diabetes, and called for curbs on marketing unhealthy food to children under a plan to cut the world's leading causes of death.
More help is needed. IDF estimates that 5.1 million people die annually because of the disease, with an average 10 million diabetes cases emerging every year. The majority of cases affects 40- to 59-year-olds, according to IDF. Every year, diabetes also leads to more than 1 million amputations, 500,000 kidney failures and 1.5 million cases of blindness, according to a slide provided by Novo Nordisk.
The spread of the disease has increased faster than the world's population, which exceeds 7 billion and has increased 2.2 percent in two years, according to U.S. Census Bureau estimates.
"More younger adults are developing diabetes," Guariguata said. "That's telling us that the pace of the epidemic is faster than the pace of change of demographics alone."
The new projections may not even be giving a full picture of the situation, according to the federation.
"These are probably substantial underestimates of what the real problem is," Paul Zimmet, honorary president of IDF and director emeritus of the Baker IDI Heart and Diabetes Institute in Melbourne, said in an interview before the announcement. "You can only work on the information that's available to work on."
Four of every five people with diabetes are in developing countries where there aren't big studies to work with, he added.
In China, recent figures showed that the epidemic being much worse than previously estimated. The most comprehensive nationwide survey for diabetes ever conducted in the Asian country showed 12 percent of adults, or 114 million people, have the disease. The finding, published Sept. 4 in the Journal of the American Medical Association, added 22 million diabetics, equivalent to the population of Australia, to a 2007 estimate. That means almost one in three diabetes sufferers globally is in China.
The China study wasn't included in the Atlas figures presented Thursday for lack of time, IDF said.
The problem is bigger in poorer regions that have fewer resources at hand to fight the diseases, for example South Africa, and where more people die of disease before the age of 60, Guariguata said.

"These are preventable deaths, premature deaths that don't have to occur," she said.

New Diabetes Testing Guidelines Set For Pregnant Women

The Endocrine Society has released a new collection of guidelines for diabetes testing in pregnant women. According to the group, only about one quarter of the gestational diabetes cases in American are diagnosed, potentially increasing the risk of complications in pregnancy.
The new guidelines are part of the Endocrine Society's Clinical Practice Guidelines (CPG). The group explained the new recommendations in a statement:
"Many women have type 2 diabetes but may not know it. Because untreated diabetes can harm both the pregnant woman and the fetus, it is important that testing for diabetes be done early on in pregnancy so that if diabetes is found, appropriate steps can be immediately undertaken to keep both the woman and her fetus healthy." 

Health Benefits Of Wild Blueberries Confirmed In New Study

Wild blueberries are a good source of phytochemicals called polyphenols, an organic compound associated with several benefits, according to research conducted at the University of Maine.
The study, published in the journal Applied Physiology, demonstrated that a diet rich in blueberries may improve conditions associated metabolic syndrome, including cardiovascular disease and diabetes.
"The metabolic syndrome (MetS) is a group of risk factors characterized by obesity, hypertension, inflammation, dyslipidemia, glucose intolerance and insulin resistance, and endothelial dysfunction," said Dr. Klimis-Zacas, a Professor of clinical nutrition at the University of Maine and a co-author of the study.
"Mets affects an estimated 37 percent of adults in the US. Many substances found in food have the potential to prevent MetS, thus reducing the need for medication and medical intervention."
The team gave lab rats the human equivalent of two cups of wild blueberries per day. The rats showed an improved balance between the relaxing and constricting factors of the vascular wall, improved blood pressure and blood flow regulation. 

Diabetes Kills One Person Every Six Seconds, Estimates Show

By Albertina Torsoli


Diabetes kills one person every six seconds and afflicts 382 million people worldwide, according to the International Diabetes Federation, which has been canvassing the help of people ranging from celebrity chef Jamie Oliver to Bob Marley’s nephew to raise awareness about the problem. 

The number of diabetes cases has climbed 4.4 percent over the past two years and is more than 5 percent of the world’s population, according to new figures the Brussels-based federation released today. The number of people affected by the disease is expected to climb 55 percent to 592 million by 2035 as factors including poor diet, a more sedentary lifestyle, increases in obesity and life expectancy fuel an epidemic, it said. There were only 285 million sufferers worldwide in 2009. 
“We haven’t seen any kind of stabilizing, any kind of reversal,” Leonor Guariguata, an epidemiologist and project coordinator for IDF’s Diabetes Atlas, published every two years, said in a phone interview. “Diabetes continues to be a very big problem and is increasing even beyond previous projections.” 

The disease, caused by a lack of insulin the body needs to convert blood sugar into energy, is becoming a financial burden on governments, and led to $548 billion in global health-care spending this year, the federation said. To counter the surge, it recommends policy makers across many sectors should devise concerted action. 

Celebrity Action 

Jamie Oliver and Charles Mattocks, Bob Marley’s nephew, are among celebrities that have been helping IDF advocate the need for healthy living. TV celebrity Oliver, who has sold more than 30 million cookbooks and owns restaurants from London to Sydney, has appeared in IDF’s magazine Diabetes Voice while Mattocks, also a chef, is currently touring the U.S. in a camper to speak about the benefits of a healthy lifestyle and eating habits. 

“It’s all about awareness, awareness and awareness,” Mike Doustdar, Senior Vice President of Novo Nordisk A/S (NOVOB), the world’s biggest insulin maker, said during a webcast co-hosted with IDF before the announcement. “Diabetes is a silent disease, so the best thing we can do about it is to talk about it.” 

The call is not going unheard. Health officials from almost 200 countries in May adopted nine targets, such as reducing average daily salt consumption by 30 percent by 2025, in a bid to fight cancer, heart disease and diabetes, and called for curbs on marketing unhealthy food to children under a plan to cut the world’s leading causes of death. 

Toll Rises 

More help is needed. IDF estimates that 5.1 million people die annually because of the disease, with an average 10 million diabetes cases emerging every year. The majority of cases affects 40- to 59-year-olds, according to IDF. Every year, diabetes also leads to more than 1 million amputations, 500,000 kidney failures and 1.5 million cases of blindness, according to a slide provided by Novo Nordisk. 

The spread of the disease has increased faster than the world’s population, which exceeds 7 billion and has increased 2.2 percent in two years, according to U.S. Census Bureau estimates. 

“More younger adults are developing diabetes,” Guariguata said. “That’s telling us that the pace of the epidemic is faster than the pace of change of demographics alone.” 

The new projections may not even be giving a full picture of the situation, according to the federation. 

Underestimated Issue? 

“These are probably substantial underestimates of what the real problem is,” Paul Zimmet, honorary president of IDF and director emeritus of the Baker IDI Heart and Diabetes Institute in Melbourne, said in an interview before the announcement. “You can only work on the information that’s available to work on.” 

Four of every five people with diabetes are in developing countries where there aren’t big studies to work with, he added. 

In China, recent figures showed that the epidemic being much worse than previously estimated. The most comprehensive nationwide survey for diabetes ever conducted in the Asian country showed 12 percent of adults, or 114 million people, have the disease. The finding, published Sept. 4 in the Journal of the American Medical Association, added 22 million diabetics, equivalent to the population of Australia, to a 2007 estimate. That means almost one in three diabetes sufferers globally is in China. 

The China study wasn’t included in the Atlas figures presented today for lack of time, IDF said. 

The problem is bigger in poorer regions that have fewer resources at hand to fight the diseases, for example South Africa, and where more people die of disease before the age of 60, Guariguata said. 

“These are preventable deaths, premature deaths that don’t have to occur,” she said. 

To contact the reporter on this story: Albertina Torsoli in Geneva at atorsoli@bloomberg.net 


To contact the editor responsible for this story: Phil Serafino at pserafino@bloomberg.net 

Diabetes and TB interlinked, say doctors

In more bad news for people diagnosed with diabetes, the lifestyle disease has now been linked to an increased incidence of tuberculosis (TB) in patients.

According to the government-run Revised National TB Control Programme (RNTCP), people with diabetes have a two-three times higher risk of TB compared to people without diabetes and about 10 per cent of TB cases globally are linked to diabetesDiabetes, which is characterized by high levels of glucose in the blood and the inability of the body to regulate blood sugar levels, is an independent risk factor for all lower respiratory tract infections, doctors said.
"The link between diabetes and tuberculosis is a recent knowledge and the subject of much research. Studies show that diabetes can lead to TB and the reverse is also true," Anoop Mishra, chairman Fortis Centre of Excellence for Diabetes Metabolic Diseases and Endocrinology (CDOC), said.
People with diabetes who are diagnosed with TB, an infectious disease of the lungs, have a higher risk of death during TB treatment and of TB relapse after treatment is over.
"Diabetes is complicated by the presence of infectious diseases like TB," Mishra added.
Doctors are, therefore, increasingly screening both diabetes and TB patients for the two diseases, he added.
The reason behind diabetes patients easily contracting TB is the low immunity in them that results in high chances of infection.
India has a high burden of both diabetes and tuberculosis. In India, there are nearly 50 million diabetics, according to the statistics of the International Diabetes Federation - a global advocate for the promotion of diabetes care, prevention and cure.
The federation had declared that India was emerging as the diabetes capital of the world.
India has approximately two to three million people infected with Tuberculosis.
According to Rajeev Chawla of the North Delhi Diabetes Centre: "Previously there was a link between diabetes and HIV, but now we can see a link between diabetes and TB. Diabetes and TB can be seen to co-exist in many cases."
"If a patient develops diabetes, it can also lead to reactivation of his or her TB which has been cured earlier.
"Diabetics should avoid contact with TB patients and always keep their blood sugar levels under check," Chawla said.
Also, in a large proportion of people, diabetes as well as TB is not diagnosed or is diagnosed too late.
Diabetes can lengthen the time to sputum culture conversion and theoretically this could lead to the development of drug resistance in TB patients, the doctor added.
Experts say the incidence of diabetes is increasing worldwide, especially in developing countries where TB is most prevalent.
Therefore, the convergence of these two epidemics is most likely to occur in the places with the least amount of healthcare resources, the doctors added.
Mishra said diabetic patients should maintain their blood sugar level in the best possible manner, exercise regularly, have proper diets and ensure that they get enough of Vitamin D

Many Diabetes Patients Don't Receive Recommended Eye Exams

As many as 25 percent of the diabetes patients in the United States may be unaware that an annual eye is recommended for people with their condition, according to a new study from researchers at the Centers for Disease Control.
The eye exams are aimed at diagnosing diabetic eye disease, which is one of the most common forms of advanced eye disease in the country. Patients of the illness often have no symptoms until the condition is fully developed, according to Dr. Carl Awh of Tennessee Retina.
"The best way to prevent unnecessary vision loss is through annual retina eye exams," Awh said. "Very often diabetic eye disease lacks any symptoms - meaning people may not know that their vision has been damaged until it's too 

FDA To Ban Remaining Trans Fats In Foods

The FDA has announced that it plans to ban partially hydrogenated vegetable oils from all food products.
Speaking at a presser, FDA commish Margaret Hamburg said that the oils "are not generally recognized as safe for use in food."
According to CDC figures, the ban could prevent an additional 7,000 deaths from heart disease each year and up to 20,000 heart attacks each year.
Consumption of trans fats is down significantly over the past decade. In 2003 the average American consumed about 4.6 grams per day, while in 2012 that number was down to one gram.
"While consumption of potentially harmful artificial trans fat has declined over the last two decades in the United States, current intake remains a significant public health concern," Hamburg added.
Partially hydrogenated vegetable oils are made when hydrogen is added to liquid oils to make solid fats. The concoction increases the shelf life and flavor of foods like frozen pizza, coffee creamer and margarine. 

Tax On Sugary Drinks Could Lower Obesity Rate

Introducing a 20 percent tax on sugary drinks may help in the battle against obesity, according to research conducted at the University of Oxford and Reading. The study, published in the BMJ, suggested such a measure could reduce the obesity rate by 1.3 percent in the U.K.
The reduction, added the study's authors, would come in the 18 to 29 age group, who also happen to be the largest consumers of sugar-sweetened drinks.
"This is important to communicate to both the public and policymakers, who see the tax as a blanket measure on obesity," wrote Adam Briggs from the British Heart Foundation health promotion research group at Oxford University."Taxation represents a measure to target population obesity, particularly among young people, but should not be seen as a panacea."
Researchers noted that the tax would raise about $442 million per year, which could be used for health awareness initiatives. 

Diabetes Risk Tied to Weight Gain in Youth

The risk of developing diabetes in adulthood is associated with weight in adolescence and weight gain during the teens and early 20s, researchers reported.

In a longitudinal cohort of teens and young adults, the timing of the weight gain also appeared to play a role in diabetes risk, according to Penny Gordon-Larsen, PhD, and colleagues at the University of North Carolina Chapel Hill.

On the other hand, hypertension in adulthood was associated just with adult body mass index (BMI), while inflammation was linked only to increasing BMI, Gordon-Larsen and colleagues reported in the November issue of Obesity.

Diabetes, insulin production and suppressed immune-supressant need


German doctors have successfully implanted insulin-producing cells in a patient with Type 1 diabetes using a specially constructed chamber system that does not require the use of immunosuppresant drugs, according to a new study.
In a paper published Monday in the journal PNAS, researchers said the islets, or clusters of cells, remained alive for 10 months and were not rejected by the 56-year-old patient's immune system. However, the implantation offered only moderate health improvements and requires further refinement.
"This approach may allow for future widespread application of cell-based therapies," wrote lead author Dr. Barbara Ludwig of the German Center for Diabetes Research in Dresden and her colleagues.
Diabetes mellitus Type 1 is an autoimmune disease that results in irreversible destruction of insulin-producing beta cells. Attempts to implant donor cells have met with two large hurdles: lack of eligible donors and the need for lifelong medication to suppress the body's immune system and prevent it from destroying the implanted cells.
The plastic disk-like device, which resembles a small puck or air-freshener, measures just more than 2 1/2 inches in diameter and more than half an inch thick. Within the container are two layers of donor cells surrounded by alginate, a semi-permeable coating that allows the cells to secrete insulin. The insulin exits the plastic disc through numerous perforations.
Two layers of cells are separated by an oxygen capsule that must be refilled daily by the patient through a tube, or port. The oxygen is able to permeate the protective alginate that surrounds the donor cells.
The patient was a 56-year-old mathemetician who has been involved with the development of other diabetese technology. He carried the implant for 10 months before it was removed and examined by doctors.
The removed cells were intact and healthy, according to researchers, and the implant itself was "well tolerated" by the patient, authors said. "Despite the absence of using any immunosuppressive agents, no signs of graft rejection or immune sensitization of the recipient were observed," the authors wrote.
The implanted cells showed evidence of insulin production but showed only a "minimal systemic effect."
Authors say that performance may be improved by adding more cells to the device and by placing it deeper in the patient's abdomen.

Diabetes Day event aims to help Montanans manage disease

October 30, 2013 8:45 pm  • 
An event geared toward helping people with diabetes successfully manage their disease will take place Saturday at Providence St. Patrick Hospital.
The free Control is the Goal Diabetes Day event begins at 7 a.m., when 20 exhibitors and vendor information tables open, and lectures are set to begin at 8 a.m. at the Broadway Building. Free breakfast is available from 7 to 9 a.m., with lunch at noon.
Diabetes is the seventh leading cause of death for Americans, said Jennifer Troupe, program coordinator for Providence Medical Group Diabetes Care and Prevention Center. The disease also is manageable if people make sure to monitor their treatment and lifestyles, she said.
“They need a lot of support and a lot of information to be able to manage it,” she said, adding that’s where Saturday’s event comes in.
Upward of 6 percent of Montanans have diabetes, which is lower than the 8.3 percent national average, Troupe said.
However, many people likely have diabetes and don’t realize it yet.
“I think all of those numbers are very much underestimated,” she said.
About 30 percent of Montanans have pre-diabetes, with the number of people with diabetes expected to jump to one in three people by 2050. Also, Native Americans are 2.3 times more likely to have a diagnosis of diabetes, she added.
Saturday’s educational event is open to anyone with diabetes or pre-diabetes, anyone who lives with someone with diabetes or anyone who just wants to learn more about the disease, managing it and preventing it.
During the event, people can get a free A1C test, which measures their three-month blood sugar average. Attendees also will hear from leading experts in the diabetes field, as well as from experts in exercise and nutrition. Additionally, a mental health professional and patient will talk about behavior changes, which is often the most difficult thing for patients to do, Troupe said.
The event concludes with a panel discussion about the health insurance exchange and its impact on diabetes patients, as well as how patients can be smart consumers.

For more details about Diabetes Day, visit montana.providence.org/campaign/pmg-montana/diabetes-day or call 329-5781.